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24, chemin de Borde Rouge -Auzeville - CS52627 31326 Castanet Tolosan cedex - France

Last update: May 2021

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Human Nutrition Unit

Zone de texte éditable et éditée et rééditée

Diet, Plant food bioactives & Vascular Health

Team leader : Christine Morand


Maintaining vascular function is essential in preserving health and healthy aging. Early vascular dysfunction is associated with initiation of atherosclerosis, CVD development and contributes to the occurrence of type 2-diabetes and cognitive decline. Therefore, it is of great importance to identify innovative and scientifically sound dietary strategies to prevent vascular dysfunctions.

NutriVasc ResContext 2019

Evidence from large prospective cohort studies have pointed out that dietary bioactive plant compounds contribute to the cardiovascular protective effects of diets rich in plant foods. However, the actual impact of most of these compounds in human and their mechanisms of action have not yet been fully established.

In this context, using a translational approach and combining classical and "omics" methodologies, the research of the NutriVasc team focuses on understanding the role of plant food bioactives in the prevention of vascular dysfunctions, with as major objectives:

- To explore the Food Metabolome to assess dietary exposures associated with plant food intake

- New mediators of the effects of diet on cardiometabolic health

- Role of plants and their bioactives on vascular and cerebrovascular function and implications for health (clinical studies with underlying mechanisms of action)

Transversally, research aims to identify the main factors responsible for interindividual variability in the response to the consumption of plant bioactives.

NutriVasc REsearch 2019

Key Words

Biomarkers exposure and health
Oxylipins and lipid mediators
Vascular function and endothelium
Dietary plant food bioactives
Targeted lipidomics
Food Metabolome
Clinical trials


Transversal Research

Plants Products and sustainable food for health