Original Publications and Reviews 2021

Mohmed AB, D Remond, A Gual-Grau, A Bernalier-Donnadille, F Capel, MC Michalsky, F Laugerette, B Cohade, N Hafnaoui, D Bechet, C Coudy-Gandhilon, M Gueugneau, J Salles, C Migne, D Dardevet, J David, S Polakof, I Savary-Auzeloux A mix of dietary fibers changes muscle phenotype by increasing mitochondrial activity and lipid oxidation in overfed mini-pigs. A Mix of Dietary Fibres Changes Interorgan Nutrients Exchanges and Muscle-Adipose Energy Handling  in Overfed Mini-Pigs. Nutrients 

Reynaud Y, Couvent A, Manach A, Forest D, Lopez M, Picque D, Souchon I, Rémond D, Dupont D. Food-dependent set-up of the DiDGI® dynamic in vitro system: Correlation with the porcine model for protein digestion of soya-based food.  Food Chem.

Reynaud Y, Buffière C, Cohade B, Vauris M, Liebermann K, Hafnaoui N, Lopez M, Souchon I, Dupont D, Rémond D. True ileal amino acid digestibility and digestible indispensable amino acid scores (DIAASs) of plant-based protein foods. Food Chem

Peyron M.A, T. Sayd, J. Sicard, P-S. Mirade, J. Pinguet, C Chambon, V Santé-Lhoutellier. Deciphering the protein digestion of meat products for the elderly by in vitro food oral processing and gastric dynamic digestion, peptidome analysis and modeling. Food and Function, Cambridge : Royal Society of Chemistry

Lepine G, Fouillet H, Remond D, Huneau J-F, Mariotti M, Polakof S A scoping review: metabolomics signatures associated with animal and plant protein intake and their potential relation to cardiometabolic risk, Advances in nutrition

Buffière C, M Hiolle, Ma Peyron, R Richard, N Meunier, C Batisse, D Rémond, D Dupont, F Nau, B Pereira, I Savary-Auzeloux. Food matrix structure (from biscuit to custard) has an impact on folate bioavailability in healthy volunteers. European Journal of Nutrition

Kim J, K Burton-Pimentel, C Fleuti, C Blaser , V Scherz, R Badertscher, C Marmonier , N Lyon-Belgy , A Caille, V Pidou , C Bertelli, G Greub , D Dardevet , J David, S Polakof, G Vergères Microbiota and metabolite modifications after dietary exclusion of dairy products and reduction in fermented foods consumption in young and older men Nutrients

Bezerra AP, Gama LT, Pereira LJ, van der Bilt A, Peyron MA, Garcia RCMR, Gonçalves TMSV. Do implant-supported prostheses affect bioavailability of nutrients of complete and partially edentulous patients? A systematic review with meta-analysis. 2021 40:3235-3249 Clinical Nutrition

Gonçalves TMSV, Schimmel M, van der Bilt A, Chen J, van der Glas HW, Kohyama K, Hennequin M, Peyron MA, Woda A, Leles CR, Pereira LJ. Consensus on the terminologies and methodologies for masticatory assessment. Journal of Oral Rehabilitation

Blanquet-Diot S, Francois O., Denis S, Hennequin,  Peyron MA. Importance of oral phase in in vitro starch digestibility related to wholegrain versus refined pastas and mastication impairment. Food Hydrocolloids

Original Publications and Reviews 2020

Dardevet D, L Mosoni, I Savary-Auzeloux , MA Peyron , S Polakof , D Rémond. Important determinants to take into account to optimize protein nutrition in the elderly: solutions to a complex equation. Proc Nutr Soc

Dopierala C , P Y Gumery, M R Frikha, J J Thiebault, S Junot, P Defaye, A Carabelli, P Tuvignon, D Remond, J Hermet, B Cohade, S Basrour, P Cinquin, F Boucher A new gastric impedancemeter for detecting the development of a visceral edema: a proof-of-concept study on an experimental endotoxemic shock  Eng Med Biol Soc

Gleize B, M Hiolle, N Meunier, B Pereira, R Richard, I Savary-Auzeloux, C Buffière, MA Peyron, C Halimi, C Caris-Veyrat, F Nau, E Reboul Food Structure Modulates the Bioavailability of Triglycerides and Vitamin D, and Partly That of Lutein: A Randomized Trial with a Crossover Design in Adults. Molecular Nutrition & Food Research

Reynaud Y, Couvent A, Manach A, Forest D, Lopez M, Picque D, Souchon I, Rémond D, Dupont D.  Food-dependent set-up of the DiDGI® dynamic in vitro system: Correlation with the porcine model for protein digestion of soya-based food.  Food Chem.

Reynaud Y, Buffière C, Cohade B, Vauris M, Liebermann K, Hafnaoui N, Lopez M, Souchon I, Dupont D, Rémond D. True ileal amino acid digestibility and digestible indispensable amino acid scores (DIAASs) of plant-based protein foods. Food Chem.

Blanquet-Diot S, Francois O., Denis S, Hennequin,  Peyron MA. Importance of oral phase in in vitro starch digestibility related to wholegrain versus refined pastas and mastication impairment. Food Hydrocolloids

Tremblay-Franco M , N Poupin, A Amiel, C Canlet, D Rémond, L Debrauwer, D Dardevet, F Jourdan  I Savary-Auzeloux, S Polakof. Postprandial NMR-based metabolic exchanges reflect impaired phenotypic flexibility across splanchnic organs in the obese Yucatan minipig.  Nutrients

Monfoulet LE, Buffière C, Istas G, Dufour C, Le Bourvellec C, Mercier S, Bayle D, Boby C, Remond D, Borel P, Rodriguez-Mateos A, Milenkovic D, Morand CEffects of the apple matrix on the postprandial bioavailability of flavan-3-ols and nutrigenomic response of apple polyphenols in minipigs challenged with a high fat meal.  Food Funct.

Reynaud Y, Buffière C, David J, Cohade B, Vauris M, Lopez M, Souchon I, Dupont D, Rémond D,. Temporal changes in postprandial intragastric pH: comparing measurement methods, food structure effects, and kinetic modelling. Food Research International

Bourdiol P, Hennequin M, Peyron MA, & Woda A.Masticatory adaptation to occlusal changes. Frontiers in Physiology

Buffière C, M Hiolle, Ma Peyron, R Richard, N Meunier, C Batisse, D Rémond, D Dupont, F Nau, B Pereira, I Savary-Auzeloux.Food matrix structure (from biscuit to custard) has an impact on folate bioavailability in healthy volunteers. European Journal of Nutrition

Linas, N, Peyron MA, Eschevins C, Hennequin M, Nicolas E, Collado V. Natural food mastication capability in preschool children according to their oral condition: a preliminary study. J Texture Studies

Peyron MA, Santé-Lhoutellier^, D.Dardevet, M.Hennequi^, D.Rémond^, O.François^, A.Woda. Addressing various challenges related to food bolus and nutrition with the AM² mastication simulator. Food Hydrocolloids

Original Publications and Reviews 2019

Poupin N, M Tremblay-Franco, A Amiel, C Canlet, D Rémond, L Debrauwer, D Dardevet, I Thiele, MK. Aurich, F Jourdan, I Savary-Auzeloux, S Polakof Arterio-venous metabolomics exploration reveals major changes across liver and intestine in the obese minipig  Scientific Reports 

Duconseille A, François O, Pereira B, Lambert C, Peyron MA, Hennequin M. Measuring the effects of in vitro mastication on bolus granulometry of shredded meat : a proposal for a new methdodological procedure. Food Research International,

Correa-Pérez A, Abraha I, Cherubini A, Collinson A, Dardevet D, de Groot LC, de van der Schueren MAE, Hebestreit A, Hickson M, Jaramillo-Hidalgo J, Lozano-Montoya I, O'Mahony D, Soiza RL, Visser M, Volkert D, Wolters M, Jentoft AJC. Efficacy of non-pharmacological interventions to treat malnutrition in older persons: A systematic review and meta-analysis. The SENATOR project ONTOP series and MaNuEL Knowledge Hub project. Ageing Res Rev.

O'Keeffe M, Kelly M, O'Herlihy E, O'Toole PW, Kearney PM, Timmons S, O'Shea E, Stanton C, Hickson M, Rolland Y, Sulmont Rossé C, Issanchou S, Maitre I, Stelmach-Mardas M, Nagel G, Flechtner-Mors M, Wolters M, Hebestreit A, De Groot LCPGM, van de Rest O, Teh R, Peyron MA, Dardevet D, Papet I, Schindler K, Streicher M, Torbahn G, Kiesswetter E, Visser M, Volkert D, O'Connor EM; MaNuEL consortium.Potentially modifiable determinants of malnutrition in older adults: A systematic review. Clinical  Nutrition.

Mosoni L, M Jarzaguet, J David, S Polakof, I Savary-Auzeloux, D Rémond and D Dardevet. Post Meal Energy Boluses Do Not Increase the Duration of Muscle Protein Synthesis Stimulation in Two Anabolic Resistant Situations.  Nutrients 2019

Le Bacquer O, Combe K, Patrac V, Ingram B, Combaret L, Dardevet D, Montaurier C, Salles J, Giraudet C, Guillet C, Sonenberg N, Boirie Y, Walrand S. 4E-BP1 and 4E-BP2 double knockout mice are protected from aging-associated sarcopenia. J Cachexia Sarcopenia Muscle.2019 Mar 29. doi: 10.1002/jcsm.12412.

Linas N, Peyron MA, Hennequin M, Eschevins C, Nicolas E, Delfosse C, Collado V. Masticatory behavior for different solid foods in preschool children according to their oral state. J Texture Stud

David J, D Dardevet; L Mosoni; I Savary-Auzeloux; S Polakof Impaired skeletal muscle branched-chain amino acids catabolism contributes to their increased circulating levels in a non-obese insulin resistant fructose-fed rat model. Nutrients

Savary-Auzeloux I., Mohamed A.B., Cohade B., Dardevet D., David J., Hafnaoui N., Migne  C. , Pujos-Guillot E., Rémond D.1, Polakof S. Overfeeding of Yucatan mini pigs altered greatly the net energy and nitrogen metabolites fluxes within and between the splanchnic and peripheral tissues to limit hyperglycemia Nutrients

Original Publications and Reviews 2018

Mohamed AB, D Rémond, C Chambon, T Sayd, M Hebraud, F Capel, B Cohade, N Hafnaoui, D Bechet, C Coudy-Gandilhon, C Migné, J David, D Dardevet, J Doré, S Polakof, I Savary-Auzeloux.    A mix of dietary fibers improves lipids handling by the liver of overfed minipigs   Journal of Nutritional Biochemistry

Zeng Y, J David, D Rémond, D Dardevet, I Savary-Auzeloux, S Polakof. Peripheral blood mononuclear cells metabolism adapted acutely to the postprandial transition and reflected mainly the adipose tissue metabolic adaptations to a high fat fed diet in minipigs. Nutrients, 2018

Jarzaguet M,  S Polakof,  J David,  C Migné,  G Joubrel,  T Efstathiou,  D Remond,  L Mosoni,   D Dardevet A meal with mixed soy/whey proteins is as efficient as a whey meal in counteracting the aged-related muscle anabolic resistance only if protein content and leucine levels are increased.Food &Function. 2018

Xia Z, J. M. Cholewa, D. Dardevet, T. Huang, Y. Zhao, H. Shang, Y. Yang,  X. Ding, C.  Zhang, H. Wang, S. Liu, Q. Su and N. E. Zanchi. Effects of oats protein supplementation on skeletal muscle damage, inflammation and performance recovery following downhill running in untrained collegiate men. Food &Function. 2018

Pujos-Guillot E, Brandolini-Bunlon M, Fouillet H, Joly C, Martin JF, Huneau JF, Dardevet D, Mariotti F. Metabolomics Reveals that the Type of Protein in a High-Fat Meal Modulates Postprandial Mitochondrial Overload and Incomplete Substrate Oxidation in Healthy Overweight Men. J Nutr. 2018

Bidu C, S Bellenger, A Spor, M Galan, A Geissler, D Dardevet, B Morio-LiondorE, Cani, L Lagrost, M Narce, J Bellenger. The transplantation of w3 PUFA-altered gut microbiota of fat-1 mice to wild-type littermates prevents obesity and associated metabolic disorders. Diabetes 2018 

Gatineau E,  Cluzet S,  Krisa S, Papet I,   Migné C,   Rémond D,  Dardevet D,  Polakof S,  Richard T  and Mosoni L. Effect of nutritional state, aging and high chronic intake of sucrose on brain protein synthesis in rats, Modulation by rutin and other micronutrients. Food&Function , 2018

Margier M, Buffière C, Goupy P, Rémond D, Halimi C, Caris C, Borel P, Reboul E. Opposite effects of the spinach food matrix on lutein bioaccessibility and intestinal uptake lead to unchanged bioavailability compared to pure lutein. Mol Nutr Food Res. 2018 

Gatineau E, S Cluzet, S Krizac, I Papet C Migné, D Rémond, D Dardevet, S Polakof, T Richard, L Mosoni.  Effect of high chronic intake of sucrose on liver metabolism in aging rats. Modulation by rutin and micronutrients. Journal of Physiology and Biochemistry, 2018. 

Mast C, Dardevet D, Papet I. Impact of medication on protein and amino acid metabolism in the elderly: the sulfur amino acid and paracetamol case. Nutr Res Rev. 2018

Polakof S, Rémond D, Bernalier-Donadille A, Rambeau M, Pujos-Guillot E, Comte B, Dardevet D, Savary-Auzeloux I. Metabolic adaptations to HFHS overfeeding: how whole body and tissues postprandial metabolic flexibility adapt in Yucatan mini-pigs. Eur J Nutr. 2018

Dufour C, Loonis M, Delosière M, Buffière C, Hafnaoui N, Santé-Lhoutellier V, Rémond D. The matrix of fruit & vegetables  modulates the gastrointestinal bioaccessibility of polyphenols and their impact on dietary protein digestibility. Food Chem, 2018

Peyron MA , Santé-Lhoutellier V , François O , Hennequin M .Oral declines and mastication deficiencies cause alteration of food bolus properties. Food Funct , 2018

Dardevet D, Mosoni L, David J, Polakof S. Fructose Feeding during the Postabsorptive State Alters Body Composition and Spares Nitrogen in Protein-Energy-Restricted Old Rats. J Nutr. 2018

Sayd  T, C. Dufour, C. Chambon, C. Buffière,  D.Remond,  V.Santé-Lhoutellier Combined in vivo and in silico approaches for predicting the release of bioactive peptides from meat digestion. Food Chemistry  2018

Polakof S, D Rémond, J David, D Dardevet, I Savary-Auzeloux. Time-course changes in circulating branched-chain amino acid levels and metabolism in obese Yucatan minipig.  Nutrition 2018

Mantha O, S. Polakof, J.F. Huneau, F. Mariotti, N. Poupin, D. Zalko, H Fouillet. Early changes in tissue amino acid metabolism and nutrient routing in rats fed a high-fat diet: evidence from natural isotope abundances as biomarkers. British Journal of Nutrition, 2018.

Zabek A, Paslawski R, Paslawska U, Wojtowicz W, Drozdz K, Polakof S, Podhorska M, Dziegiel P, Mlynarz P, Szuba A  The influence of different diets on metabolism and atherosclerosis processes - a porcine model. Blood serum, urine and tissues 1H NMR metabolomics targeted analysis. 2017, PlosONE

Barquissau, V ; F Capel.; D Dardevet; C Feillet-Coudray; A Gallinier.; MA Chauvin; J Rieusset; B Morio.Reactive oxygen species enhance mitochondrial function, insulin sensitivity and glucose uptake in skeletal muscle of senescence accelerated prone mice SAMP8. 2017,  Free Radical Biology and Medicine

Revel A, M Jarzaguet, MA Peyron, I Papet, N Hafnaoui, C Migné, L Mosoni, S Polakof, I Savary-Auzeloux, D Rémond and D Dardevet. At same leucine intake, a whey/plant protein blend is not as effective as whey to initiate a transient post prandial muscle anabolic response during a catabolic state in mini pigs. 2017, PlosONE

Buffière C, C Gaudichon, N Hafnaoui, C Migné, V Scislowsky, N Khodorova, L Mosoni, A Blot, Y Boirie, D Dardevet, V Santé-Lhoutellier, D Rémond. In the elderly, meat protein assimilation from rare meat is lower than that from meat that is well done. 2017, American Journal of Clinical Nutrition

Mast C., C. Pourpre, G. Voyard , D. Rémond, C. Migné, D. Centeno, D. Dardevet, I. Savary-Auzeloux  and I. Papet. Dietary supplementation with cysteine prevents adverse metabolic outcomes of repeated cures with paracetamol in old rats. 2017, British Journal of Nutrition

Louessard M, Bardou I, Lemarchand E, Thiebaut AM, Parcq J, Leprince J, Terrisse A, Carraro V, Fafournoux P, Bruhat A, Orset C, Vivien D, Ali C, Roussel BD. Activation of cell surface GRP78 decreases endoplasmic reticulum stress and neuronal death. 2017 Cell Death Differ. Sep;24(9):1518-1529.

Mesclon F, Lambert-Langlais S, Carraro V, Parry L, Hainault I, Jousse C, Maurin AC, Bruhat A, Fafournoux P, Averous J. Decreased ATF4 expression as a mechanism of acquired resistance to long-term amino acid limitation in cancer cells. 2017 Oncotarget Apr 18;8(16):27440-27453.

Bruhat A, Fafournoux P. The CCAAT/enhancer-binding protein-ATF response elements-luciferase mouse model, an innovative tool to monitor the integrated stress response pathway in vivo. 2017 Curr Opin Clin Nutr Metab Care May;20(3):175-180.

Bruhat A, Chaveroux C, Carraro V, Jousse C, Averous J, Maurin AC, Parry L, Mesclon F, Muranishi Y, Baril P, Do Thi A, Ravassard P, Mallet J, Fafournoux P. [Tuning transgene expression with an artificial diet: a compelling resource in gene therapy]. 2017 Med Sci (Paris) Feb;33(2):136-139.

Dumortier O, Roger E, Pisani DF, Casamento V, Gautier N, Lebrun P, Johnston H, Lopez P, Amri EZ, Jousse C, Fafournoux P, Prentki M, Hinault C, Van Obberghen E. Age-Dépendent Control of Energy Homeostasis by Brown Adipose Tissue in Progeny Subjected to Maternal Diet-Induced Fetal Programming.  2017 Diabètes Mar;66(3):627-639.

Cholewa J,  D DardeveT,  Lima Soares F, , K Pessôa, PH Oliveira,  J R Dos Santos Pinho, H Nicastro, Z Xia, C Emmanuel Torres Cabido,NE Zanchi. Dietary proteins and amino acids in the control of the muscle mass during immobilization and aging: Role of the MPS response. 2017 Aminoacids  May;49(5):811-820 

Gatineau E, S Polakof, D Dardevet, L Mosoni. Similarities and interactions between the aging process and high chronic intake of added sugars. Nutrition Research Reviews, 2017 17:1-17

BORDONI A, F DANESI, D DARDEVET, D GILLE, L AUTHOR, C NUNES DOS SANTOS, P PINTO, R RE, D REMOND, D SHAKAR, G VERGÈRES. Dairy Products and Inflammation: A Review of the Clinical Evidence Crit Rev Food Sci Nutr. 2017, 57, 2497-2525  

Arufe S, Chiron H, Doré J, Savary-Auzeloux I, Saulnier L, Della Valle G. Processing and rheological properties of wheat flour dough and bread containing high levels of soluble fibres blends. Food research International. 2017 Jul;97:123-132  

Kraft G, KC. Coate,  J Winnick, D Dardevet, PE. Donahue, AD. Cherrington, PE. Williams and MC Moore. Glucagon’s effect on liver protein metabolism in vivo. American Journal of Physiology.  May 23:ajpendo.00045.2017.

Verney J, V Martin, S Ratel, V Chavanelle, M Bargetto,M Etienne, E Chaplais, P Le Ruyet, C Bonhomme, L Combaret, C Guillet, N Boisseau, P Sirvent and D Dardevet. Soluble milk proteins improve muscle mass recovery after immobilization-induced muscle atrophy in old rats but do not improve muscle functional property restoration. The journal of Nutrition, Health & Aging. 2017

Bohn T, Carriere F, Day L, Deglaire A, Egger L, Freitas D, Golding M, Le Feunteun S,Macierzanka A, Menard O, Miralles B, Moscovici A, Portmann R, Recio I, Rémond D, Santé-Lhoutelier V, Wooster TJ, Lesmes U, Mackie AR, Dupont D. Correlation between in vitro and in vivo data on food digestion. What can we predict with static in vitro digestion models? Crit Rev Nutr Food Sci 2017

Thorning TK, Bertram HC, Bonjour JP, de Groot L, Dupont D, Feeney E, Ipsen R, Lecerf JM, Mackie A, McKinley M, Michalski MC, Rémond D, Risérus U, Soedamah-Muthu S, Tholstrup T, Weaver C, Astrup A, Givens I, 2017. Whole dairy matrix or single nutrients in assessment of health effects: current evidence and knowledge gaps. Am J Clin Nutr , 2017, May;105(5):1033-1045

Chavanelle V, N Boisseau, YF Otero, L Combaret, D Dardevet, C Montaurier, G Delcros, S Peltier, P Sirvent Effects of high-intensity interval training and moderate-intensity continuous training on glycaemic control and skeletal muscle mitochondrial function in db/db mice. Scientific reports Mar 16;7(1):204