Know more

About cookies

What is a "cookie"?

A "cookie" is a piece of information, usually small and identified by a name, which may be sent to your browser by a website you are visiting. Your web browser will store it for a period of time, and send it back to the web server each time you log on again.

Different types of cookies are placed on the sites:

  • Cookies strictly necessary for the proper functioning of the site
  • Cookies deposited by third party sites to improve the interactivity of the site, to collect statistics

Learn more about cookies and how they work

The different types of cookies used on this site

Cookies strictly necessary for the site to function

These cookies allow the main services of the site to function optimally. You can technically block them using your browser settings but your experience on the site may be degraded.

Furthermore, you have the possibility of opposing the use of audience measurement tracers strictly necessary for the functioning and current administration of the website in the cookie management window accessible via the link located in the footer of the site.

Technical cookies

Name of the cookie


Shelf life

CAS and PHP session cookies

Login credentials, session security



Saving your cookie consent choices

12 months

Audience measurement cookies (AT Internet)

Name of the cookie


Shelf life


Trace the visitor's route in order to establish visit statistics.

13 months


Store the anonymous ID of the visitor who starts the first time he visits the site

13 months


Identify the numbers (unique identifiers of a site) seen by the visitor and store the visitor's identifiers.

13 months

About the AT Internet audience measurement tool :

AT Internet's audience measurement tool Analytics is deployed on this site in order to obtain information on visitors' navigation and to improve its use.

The French data protection authority (CNIL) has granted an exemption to AT Internet's Web Analytics cookie. This tool is thus exempt from the collection of the Internet user's consent with regard to the deposit of analytics cookies. However, you can refuse the deposit of these cookies via the cookie management panel.

Good to know:

  • The data collected are not cross-checked with other processing operations
  • The deposited cookie is only used to produce anonymous statistics
  • The cookie does not allow the user's navigation on other sites to be tracked.

Third party cookies to improve the interactivity of the site

This site relies on certain services provided by third parties which allow :

  • to offer interactive content;
  • improve usability and facilitate the sharing of content on social networks;
  • view videos and animated presentations directly on our website;
  • protect form entries from robots;
  • monitor the performance of the site.

These third parties will collect and use your browsing data for their own purposes.

How to accept or reject cookies

When you start browsing an eZpublish site, the appearance of the "cookies" banner allows you to accept or refuse all the cookies we use. This banner will be displayed as long as you have not made a choice, even if you are browsing on another page of the site.

You can change your choices at any time by clicking on the "Cookie Management" link.

You can manage these cookies in your browser. Here are the procedures to follow: Firefox; Chrome; Explorer; Safari; Opera

For more information about the cookies we use, you can contact INRAE's Data Protection Officer by email at or by post at :


24, chemin de Borde Rouge -Auzeville - CS52627 31326 Castanet Tolosan cedex - France

Last update: May 2021

Menu Logo Principal logo Université Clermont Auvergne & associés

Human Nutrition Unit

Zone de texte éditable et éditée et rééditée


Selected publications

Vitamin D status modulates mitochondrial oxidative capacities in skeletal muscle: role in sarcopenia. Salles J, Chanet A, Guillet C, Vaes AM, Brouwer-Brolsma EM, Rocher C, Giraudet C, Patrac V, Meugnier E, Montaurier C, Denis P, Le Bacquer O, Blot A, Jourdan M, Luiking Y, Furber M, Van Dijk M, Tardif N, Yves Boirie Y, Walrand S. Commun Biol. 2022 Nov 24;5(1):1288. doi: 10.1038/s42003-022-04246-3. Abstract

Deleterious Effect of High-Fat Diet on Skeletal Muscle Performance Is Prevented by High-Protein Intake in Adult Rats but Not in Old Rats. Poggiogalle E, Rossignon F, Carayon A, Capel F, Rigaudière JP, De Saint Vincent S, Le Bacquer O, Salles J, Giraudet C, Patrac V, Lebecque P, Walrand S, Boirie Y, Martin V, Guillet C. Front Physiol doi: 10.3389/fphys.2021.749049. Abstract

Targeting the gut to prevent and counteract metabolic disorders and pathologies during aging. Milenkovic D, Capel F, Combaret L, Comte B, Dardevet D, Evrard B, Guillet C, Monfoulet LE, Pinel A, Polakof S, Pujos-Guillot E, Rémond D, Wittrant Y, Savary-Auzeloux I. Crit Rev Food Sci Nutr doi: 10.1080/10408398.2022.2089870. Abstract

Characterization of the Skeletal Muscle Proteome in Undernourished Old Rats. Barbé C, Salles J, Chambon C, Giraudet C, Sanchez P, Patrac V, Denis P, Boirie Y, Walrand S, Gueugneau M. Int J Mol Sci. 2022 Apr 26:23(9):4762. doi: 10.3390/ijms23094762. Abstract

Alterations of the endocannabinoid system and circulating and peripheral tissue levels of endocannabinoids in sarcopenic rats. Le Bacquer O, Salles J, Piscitelli F, Sanchez P, Martin V, Montaurier C, Di Marzo V, Walrand S. J Cachexia Sarcopenia Muscle. 2021 Dec 2. doi: 10.1002/jcsm.12855. Abstract

Muscle Proteomic and Transcriptomic Profiling of Healthy Aging and Metabolic Syndrome in Men. Gueugneau M, Coudy-Gandilhon C, Chambon C, Verney J, Taillandier D, Combaret L, Polge C, Walrand S, Roche F, Barthélémy JC, Féasson L, Béchet D. Int J Mol Sci. 2021 Apr 19;22(8):4205. doi: 10.3390/ijms22084205. Abstract

Transgenerational supplementation with eicosapentaenoic acid reduced the metabolic consequences on the whole body and skeletal muscle in mice receiving an obesogenic diet. Pinel A, Rigaudière JP, Jouve C, Montaurier C, Jousse C, LHomme M, Morio B, Capel F. Eur J Nutr. 2021 Feb 4. doi: 10.1007/s00394-021-02502-6. Abstract

An Integrated Analysis of miRNA and Gene Expression Changes in Response to an Obesogenic Diet to Explore the Impact of Transgenerational Supplementation with Omega 3 Fatty Acids. Corral-Jara KF, Cantini L, Poupin N, Ye T, Rigaudière JP, De Saint Vincent S, Pinel A, Morio B, Capel F. Nutrients. 2020 Dec 17;12(12):3864.doi: 10.3390/nu12123864. Abstract

Acute rimonabant treatment promotes protein synthesis in C2C12 myotubes through a CB1-independent mechanism. Le Bacquer O, Lanchais K, Combe K, Van Den Berghe L, Walrand S. J Cell Physiol doi: 10.1002/jcp.30034. Abstract

Could Omega 3 Fatty Acids Preserve Muscle Health in Rheumatoid Arthritis? Lanchais K, Capel F, Tournadre A. Nutrients doi: 10.3390/nu12010223. Abstract

4E-BP1 and 4E-BP2 double knockout mice are protected from aging-associated sarcopenia. Le Bacquer O, Combe K, Patrac V, Ingram B, Combaret L, Dardevet D, Montaurier C, Salles J, Giraudet C, Guillet C, Sonenberg N, Boirie Y, Walrand S. J Cachexia Sarcopenia Muscle. 2019 Mar 29. doi: 10.1002/jcsm.12412. Abstract

Modulation of Insulin Resistance and the Adipocyte-Skeletal Muscle Cell Cross-Talk by LCn-3PUFA. Pinel A, Rigaudière JP, Jouve C, Capel F. Int J Mol Sci. 2018 Sep 15;19(9). pii: E2778. doi: 10.3390/ijms19092778. Abstract

Fast digestive proteins and sarcopenia of aging. Boirie Y, Guillet C. Curr Opin Clin Nutr Metab Care. 2018 Jan;21(1):37-41. Abstract

Reactive oxygen species enhance mitochondrial function, insulin sensitivity and glucose uptake in skeletal muscle of senescence accelerated prone mice SAMP8. Barquissau V, Capel F, Dardevet D, Feillet-Coudray C, Gallinier A, Chauvin MA, Rieusset J, Morio B. Free Radic Biol Med. 2017 Dec;113:267-279. Abstract

Fast digestive, leucine-rich, soluble milk proteins improve muscle protein anabolism, and mitochondrial function in undernourished old rats. Salles J, Chanet A, Berry A, Giraudet C, Patrac V, Domingues-Faria C, Rocher C, Guillet C, Denis P, Pouyet C, Bonhomme C, Le Ruyet P, Rolland Y, Boirie Y, Walrand S. Mol Nutr Food Res. 2017 Nov;61(11). doi: 10.1002/mnfr.201700287. Abstract

Vitamin D supplementation restores the blunted muscle protein synthesis response in deficient old rats through an impact on ectopic fat deposition. Chanet A, Salles J, Guillet C, Giraudet C, Berry A, Patrac V, Domingues-Faria C, Tagliaferri C, Bouton K, Bertrand-Michel J, Van Dijk M, Jourdan M, Luiking Y, Verlaan S, Pouyet C, Denis P, Boirie Y, Walrand S. J Nutr Biochem. 2017 Aug;46:30-38. Abstract

Muscle metabolic alterations induced by genetic ablation of 4E-BP1 and 4E-BP2 in response to diet-induced obesity. Le Bacquer O, Combe K, Montaurier C, Salles J, Giraudet C, Patrac V, Domingues-Faria C, Guillet C, Louche K, Boirie Y, Sonenberg N, Moro C, Walrand S. Mol Nutr Food Res. 2017 Sep;61(9). doi: 10.1002/mnfr.201700128. Abstract

Sarcopenia in older mice is characterized by a decreased anabolic response to a protein meal. van Dijk M, Nagel J, Dijk FJ, Salles J, Verlaan S, Walrand S, van Norren K, Luiking Y. Arch Gerontol Geriatr. 2017 Mar - Apr;69:134-143. Abstract

Oleate dose-dependently regulates palmitate metabolism and insulin signaling in C2C12 myotubes. Capel F, Cheraiti N, Acquaviva C, Hénique C, Bertrand-Michel J, Vianey-Saban C, Prip-Buus C, Morio B. Biochim Biophys Acta. 2016 Dec;1861(12 Pt A):2000-2010. Abstract

GPR40 mediates potential positive effects of a saturated fatty acid enriched diet on bone. Philippe C, Wauquier F, Landrier JF, Bonnet L, Miot-Noirault E, Rochefort GY, Sadoine J, Asrih M, Jornayvaz FR, Bernalier A, Coxam V, Wittrant Y. Mol Nutr Food Res. 2017 Feb;61(2). doi: 10.1002/mnfr.201600219. Abstract

Full list of publication (Pubmed List)