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The ASMS team was present at the congress of the Journées Francophones de Nutrition (Toulouse) through different oral communications and eposters:

- Yves Boirie: Sarcopenia: From protein metabolism to clinical deficit.
- Yves Boirie: Recommendations for the diagnosis of sarcopenic obesity: a decisive step.
- Lisar Guerrier: Relationship between BMI, adiposity and mitochondrial respiration in human white adipose tissue.
- Marine Gueugneau: Nutritional value of wheat and pea sprouts on protein and lipid metabolism in growing rats.
- Olivier Le Bacquer: Cannabidiol prevents cisplatin-induced atrophy in a model of myotubes in culture.
- Christophe Montaurier: Utility of calorimetric chambers to measure changes in energy expenditure in patients with Parkinson's disease.
- Alexande Pinel: Does muscle "functional" age differ from chronological age in severely obese adult patients at risk for sarcopenic obesity?
- Jérémie Talvas: Excessive eccentric training in vitamin D-deficient mice leads to loss of physical capacity, muscle atrophy and systemic inflammation.
- Stéphane Walrand: Muscle aging: beyond protein intake..
- Stéphane Walrand: From the bench to health policy: example of vitamin D. Basic aspects (in vitro studies, pre-clinical models).

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Christophe Montaurier went to Québec (Canada) for the 5th Recent Advances & Controversies in the Measurement of Energy Metabolism (RACMEM) to present his work:

- Usefulness of calorimetric chambers for measuring changes of energy expenditure in Parkinson disease patients.
- Measurement of energy expenditure of yellow mealworms in a mass rearing context.

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The ASMS team was present at the European Society for Parenteral and Enteral Nutrition congress in Vienna (Austria) through different oral communications and eposters:

- Elizabeth Benz: Sarcopenic obesity and all cause mortality in middle aged and older people: a population based study.
- Elizabeth Benz: Prevalence of sarcopenic obesity according to  the definition and diagnosis criteria of ESPEN/EASO consensus statement: The Rotterdam study.
- Aurélien Brun: Prevention of muscle atrophy and myosteatosis by polyunsaturated fatty acids.
- Olivier Le Bacquer: Cannabidiol prevents cisplatin-induced atrophy in a model of myotubes in culture.
- Alexande Pinel: Identification of factors related with sarcopenic obesity phenotype: An extensive literature based analysis in the SO-NUTS european project.

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Christophe Montaurier went to Québec (Canada) for the 4th International Congress: Insects to Feed the World, to present a poster on the determination of the calorimetric potential of mealworms in a mass rearing context

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RH: The ASMS team is expanding…

The ASMS team is growing, as 2 new PhD students have joined our ranks. It is with pleasure that we welcome

Lisa Guerrier. Lisa holds a Master's degree in "Nutrition Health Innovation, Human Health Nutrition" (UCA). She obtained a funding from the Doctoral School of UCA. She is starting a thesis on the Role of mitochondria in human adipose tissue in the context of body composition modification during chronic diseases. This work is supervised by Ruddy Richard and Corinne Malpuèch-Brugère.

Thesis summary

Mitochondria play a key role in the maintenance of energy homeostasis in tissues including adipose tissue. If quantitative (number of mitochondria) or qualitative mitochondrial dysfunctions have been well studied in human skeletal muscle tissue, they are poorly documented in adipose tissue, especially depending on the origin and location (subcutaneous or visceral epiplonic adipose tissue). A key role of adipose tissue mitochondria is increasingly suggested in the development of metabolic diseases, notably obesity (fat mass gain), type 2 diabetes and cancer (fat mass loss). The hypothesis is that mitochondrial dysfunction could lead to adverse effects on adipocyte differentiation, lipid metabolism, insulin sensitivity, oxidative capacity and thermogenesis. The objective of this thesis will be to characterize the function of mitochondria according to the origin of subcutaneous and visceral adipose tissue in patients with metabolic dysfunctions, and thus to understand the impact of weight gain or loss on the metabolic activity of these tissues.

Aurélien Brun. Aurélien holds a Master's degree in "Nutrition Health Innovation, Human Health Nutrition" (UCA). He obtained a funding from Clermont Auvergne Métropole. He is starting his thesis on the Prevention of muscle atrophy and myosteatosis by omega-3 fatty acids. This work is supervised by Fédéric Capel and Vera Mazurak. Aurélien will complete half of his thesis in the ASMS team and the other half at the University of Alberta (Canada).

Thesis summary

Healthy aging has become a major societal issue due to the current demographic dynamics of Western countries. Periods of chronic or acute loss of muscle capital lead to an increase in the length of hospitalization and a deterioration in the prognosis of weakened individuals. This is why maintaining muscle mass is one of the main determinants of autonomy in aging people. During my PhD in collaboration with INRAe/UCA & Cross Cancer Institute/UofA, I am interested in the fundamental biological processes leading to the accumulation of toxic lipids in the muscle called myosteatosis. The objective is to understand how and why long-chain unsaturated fatty acids of marine origin allow to preserve the integrity of the muscle during episodes of acute lipotoxicity occurring in many pathological conditions (Cancer, Diabetes, Obesity, Rheumatoid Arthritis).