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24, chemin de Borde Rouge -Auzeville - CS52627 31326 Castanet Tolosan cedex - France

Last update: May 2021

Menu Logo Principal logo Université Clermont Auvergne & associés

Human Nutrition Unit

Zone de texte éditable et éditée et rééditée

Dr Yohann Wittrant


Researcher (Ph.D Cellular and Molecular Biology)


photo yohann wittrant

Phone: +33(0)6 82 29 72 71

Field of Research

Osteo-articular functions, Mobility, Bone biology, Health, Nutrition

Research Activities

We aim at developing innovative, translational and collaborative science-based nutritional approaches targeting new pathways involved in locomotor dysfunction (most notably osteo-articular tissues) to preserve mobility and improve healthy life expectancy;

Selected publications

Bani Hassan E, Alderghaffar M, Wauquier F, Coxam V, Demontiero O, Vogrin S, Wittrant Y, Duque G. The effects of dietary fatty acids on bone, hematopoietic marrow and marrow adipose tissue in a murine model of senile osteoporosis. Aging (Albany NY). 2019 Sep 25;11(18):7938-7947.

Wauquier F, Daneault A, Granel H, Prawitt J, Fabien Soulé V, Berger J, Pereira B, Guicheux J, Rochefort GY, Meunier N, Blot A, Wittrant Y. Human Enriched Serum Following Hydrolysed Collagen Absorption Modulates Bone Cell Activity: from Bedside to Bench and Vice Versa. Nutrients. 2019 May 31;11(6).

Granel H, Bossard C, Nucke L, Wauquier F, Rochefort GY, Guicheux J, Jallot E, Lao J, Wittrant Y. Optimized Bioactive Glass: the Quest for the Bony Graft. Adv Healthc Mater. 2019 Jun;8(11):e1801542.

Daneault A, Prawitt J, Fabien Soulé V, Coxam V, Wittrant Y. Biological effect of hydrolyzed collagen on bone metabolism. Crit Rev Food Sci Nutr. 2017 Jun 13;57(9):1922-1937.

Philippe C, Wauquier F, Landrier JF, Bonnet L, Miot-Noirault E, Rochefort GY, Sadoine J, Asrih M, Jornayvaz FR, Bernalier A, Coxam V, Wittrant Y. GPR40 mediates potential positive effects of a saturated fatty acid enriched diet on bone. Mol Nutr Food Res. 2017 Feb;61(2).

Patents and contribution to innovation

# 1 - Patent 1354275 RS WITTRANT: "Use of two compounds for the treatment and / or prevention of bone disorders" Léotoing L, Coxam V, Wittrant Y. International Deposit: No. 14 729 418.5 (2014) National filing: Patent no ° 13 54275 (2013)

# 2 Patent FR18 / 60557: "Controlled Porosite Implant in Hybrid Biomaterial Doped with Osteoinductive Nutrients" Granel H, Bossard C, J, Jallot E, Lao J, Wittrant Y. National Depot: 15/11/2018 under number No. FR18 / 60557

# 3 Declaration of Invention and Valuable Outcomes (DI-RV # 18-00058 INRA). Base of the upcoming creation of the Clinic'n'Cell start-up. This project is followed by the BUSI incubator.

Curriculum Vitae

Researcher (2008-) Nutrition, Metabolism and bone, INRA UMR1019 Human Nutrition Unit, Clermont-Ferrand – France

Business School Certification (2019), Ecole Supérieure de Commerce de Clermont-Ferrand

Accreditation to supervise research (Habilitation à Diriger des Recherches) - (2010) – Université d’Auvergne - Title : « Nutrition, lipids and bone ».

2nd Post-doctoral position. (2007-2008) INSERM U791, Dental School, Nantes – France; “Oxidative stress and mineralizing cell differentiation”.

MBA (1 option of the continuing training), (2008) University of Nantes, Economy and Management Center, Nantes – France; “Management of innovative projects”

1st Post-doctoral position. (2006-2007) University of Texas Health Science Center at San Antonio, Department of Pathology – USA; “Diabetes, oxidative stress and bone pathology”. Sponsored by a NIH grant.

Ph D. (2003-2005) INSERM U957, Faculty of Medicine, Nantes – France; “New opportunities in bone tumor therapeutic design”.

Master (2002) Bone and Joint Biology - Paris VII University, France.

Awards and Grants

”Prime d’excellence 2B INRA” in 2013

”Prime d’excellence 2C INRA” in 2017

Start-up project: Clinic'n'Cell. Clermont-Innovation-Création program.