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24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

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Human Nutrition Unit

Zone de texte éditable et éditée et rééditée

Martine DUCLOS, PhD, MD


Email: contact
Tél: +33(0)4 73 75 16 64


Because of the major role of the muscle within the body, the objective is to maintain health and well-being by combining nutrition and physical activity, to maintain muscle mass and qualities, and therefore mobility, and limit co-morbidities

Research Activities

Because of the major role of the muscle within the body, the objective is to maintain health and well-being by combining nutrition and physical activity, to maintain muscle mass and qualities, and therefore mobility, and limit co-morbidities. Two main axes are defined:

1) Increase or even maintain muscle mass and quality, as well as physical fitness in different physiological (aging) or pathological situations accompanied by metabolic disorders (type 2 diabetes, obesity, cancer) in relation to the level of total physical activity, type and intensity of physical activity and the total time spent in sedentary behaviors. The aim is to focus on reducing the amount of time spent in sedentary behaviors and replacing them with either a low-intensity PA or even a moderate PA at a later date

2) Develop innovative strategies using new information and communication technologies, to establish and maintain long-term physical activity in subjects with chronic conditions that affect mobility. The secondary objectives are to evaluate variations in physical activity and sedentary behaviors over time and the impact of a decrease in sedentary time on quality of life, physical performances and cardiometabolic co-morbidities. The hypothesis is that the use of a smartphone with an objective measure of low-intensity physical activity and sedentary behaviors should make it possible to modify behaviors in a sustainable way and thus favor the follow-up of recommendations more adapted to this sedentary population. inactive. As has been demonstrated in healthy subjects, significant effects on health and co-morbidities can be expected, with greater involvement of patients.


  • Thivel D, Doucet E, Julian V, Cardenoux C, Boirie Y, Duclos M. Nutritional compensation to exercise- vs. diet-induced acute energy deficit in adolescents with obesity. Physiol Behav. 2017;176:159-64
  • Duclos M, G. Fleury, P. Lacomme, R. Phan, L. Ren, S. Rousset. An Acceleration Vector Variance based Method for Energy Expenditure Estimation in Real-Life Environment with a Smartphone/Smartwatch Integration. Expert Systems With Applications, 2016, doi 10.1016/j.eswa.2016.07.021
  • Duclos M, Tabarin A. Exercise and the Hypothalamo-Pituitary-Adrenal axis. Front Horm Res 2016, 47, 12-26
  • Lanhers,C., Duclos,M., Guttmann,A., Coudeyre,E., Pereira,B., & Ouchchane,L.  General Practitioners' Barriers to Prescribe Physical Activity: The Dark Side of the Cluster Effects on the Physical Activity of Their Type 2 Diabetes Patients. PLoSONE. Oct 15; 10 (10): e0140429, 2015
  • Duclos M, Ouerdani A, Mormède P, Konsman JP. Food-restriction-induced hyperactivity: addiction or fleeing famine? Psychoneuroendocrinology 38(6) 884-97, 2013
  • Duclos M, Coudeyre E, Ouchchane L. General practioners' barriers to physical activity negatively influence type 2 diabetes mellitus patients' involvement in regular physical activity. Diabetes Care 34 (7): e122, 2011

Curriculum vitae

Professeur des Universités-Praticien Hospitalier (Physiologie), chef du service de Médecine du Sport et des Explorations Fonctionnelles, CHU G. Montpied, Clermont-Ferrand

Medical Doctor, Rennes, France, 1982-1989
Specialization in Endocrinology, Metabolism and Diabetology, Bordeaux, France, 1990-1994
Ph D in Exercise Human Physiology, Bordeaux, France, 1994-1997
Post Doctoral Study: University of Montreal: Pr F. Peronn

Activity of expertise
- Scientific Expert for the National Institute for Medical Research (INSERM) and the Ministry of Sport and Health on the effects of exercise on Health (July 2006-October 2007)
- French Speaking Association for Diabetes and Metabolic Diseases Research: head of the study group on diabetes and physical activity (2010-present)
-European Commission: French expert in the focal group for the Health Enhancing Physical Activity policies (2014-present)
- French National Agency for Sanitary Security of food, Environnement and Work (ANSES): member of the experts group "National Plan for Nutrition and Health: review of the references for physical activity and health" (november 2013-december 2015)
- National Institute of Cancer: member of the experts group « Physical activity during and after cancer » (september 2013-june 2016)
-Scientific advisor of the French ministry of Sport for sport, physical activity and Health (2012-present)
-President of the French National observatory of Physical Activity and Sedentarity (oct 2015-present)
-Member of the member of the experts group of the World AntiDoping Agency for Glucocorticoid list (feb 2016-present)