Know more

About cookies

What is a "cookie"?

A "cookie" is a piece of information, usually small and identified by a name, which may be sent to your browser by a website you are visiting. Your web browser will store it for a period of time, and send it back to the web server each time you log on again.

Different types of cookies are placed on the sites:

  • Cookies strictly necessary for the proper functioning of the site
  • Cookies deposited by third party sites to improve the interactivity of the site, to collect statistics

Learn more about cookies and how they work

The different types of cookies used on this site

Cookies strictly necessary for the site to function

These cookies allow the main services of the site to function optimally. You can technically block them using your browser settings but your experience on the site may be degraded.

Furthermore, you have the possibility of opposing the use of audience measurement tracers strictly necessary for the functioning and current administration of the website in the cookie management window accessible via the link located in the footer of the site.

Technical cookies

Name of the cookie


Shelf life

CAS and PHP session cookies

Login credentials, session security



Saving your cookie consent choices

12 months

Audience measurement cookies (AT Internet)

Name of the cookie


Shelf life


Trace the visitor's route in order to establish visit statistics.

13 months


Store the anonymous ID of the visitor who starts the first time he visits the site

13 months


Identify the numbers (unique identifiers of a site) seen by the visitor and store the visitor's identifiers.

13 months

About the AT Internet audience measurement tool :

AT Internet's audience measurement tool Analytics is deployed on this site in order to obtain information on visitors' navigation and to improve its use.

The French data protection authority (CNIL) has granted an exemption to AT Internet's Web Analytics cookie. This tool is thus exempt from the collection of the Internet user's consent with regard to the deposit of analytics cookies. However, you can refuse the deposit of these cookies via the cookie management panel.

Good to know:

  • The data collected are not cross-checked with other processing operations
  • The deposited cookie is only used to produce anonymous statistics
  • The cookie does not allow the user's navigation on other sites to be tracked.

Third party cookies to improve the interactivity of the site

This site relies on certain services provided by third parties which allow :

  • to offer interactive content;
  • improve usability and facilitate the sharing of content on social networks;
  • view videos and animated presentations directly on our website;
  • protect form entries from robots;
  • monitor the performance of the site.

These third parties will collect and use your browsing data for their own purposes.

How to accept or reject cookies

When you start browsing an eZpublish site, the appearance of the "cookies" banner allows you to accept or refuse all the cookies we use. This banner will be displayed as long as you have not made a choice, even if you are browsing on another page of the site.

You can change your choices at any time by clicking on the "Cookie Management" link.

You can manage these cookies in your browser. Here are the procedures to follow: Firefox; Chrome; Explorer; Safari; Opera

For more information about the cookies we use, you can contact INRAE's Data Protection Officer by email at or by post at :


24, chemin de Borde Rouge -Auzeville - CS52627 31326 Castanet Tolosan cedex - France

Last update: May 2021

Menu Logo Principal logo Université Clermont Auvergne & associés

Human Nutrition Unit

Zone de texte éditable et éditée et rééditée

Frédéric CAPEL, PhD


Email : contact
Tel : +33(0)4 73 17 82 67

Frédéric Capel

I've obtained a PhD (2004) in Life Sciences on the relationship between the loss of skeletal muscle with aging and the alterations in mitochondrial functions (energy & reactive oxygen species productions). Between 2005 and 2010, I had the opportunity to be introduced to functional genomic to study the regulation of gene expression in insulin-sensitive tissues depending on population (obese, elderly people) nutritional status. In 2010, I joined the Human Nutrition Unit of the INRA as a research scientist. I work on nutritional strategies based on dietary fats to prevent metabolic disorders linked to excess body fat. It is now well established that the quality of dietary fatty acids is crucial in the prevention of many pathologies. Some classes of fatty acids could help at preventing the accumulation of deleterious lipid metabolites and some metabolic disorders or inflammation. I used both in vitro (cellular approaches) and in vivo/physiological (animal models, human interventions) to understand and modify the relationship between lipid metabolism, adipose tissue and skeletal muscle physiology.

Research Activities

Ongoing projects are related to the effect of omega 3 PUFAs in the prevention of obesity-associated metabolic disorders:

Prevention of the accumulation of toxic lipid metabolites in skeletal muscle (phospholipids, diacylglycerols, ceramides) and the progression of inflammation

Impact on the development of adipose tissue and modulation of its metabolism

In vitro analysis of the physiologic/metabolic relationship between adipose and muscle cells

Other projects concerned the identification of lipid markers (fatty acids, phospholipids) of metabolic disorders (in relation with clinicians) or specific dietary intakes.


  • Capel, F., C. Acquaviva, et al. (2015). "DHA at nutritional doses restores insulin sensitivity in skeletal muscle by preventing lipotoxicity and inflammation." J Nutr Biochem 26(9): 949-959.
  • Capel, F., N. Cheraiti, et al. (2016). "Oleate dose-dependently regulates palmitate metabolism and insulin signaling in C2C12 myotubes." Biochim Biophys Acta 1861(12 Pt A): 2000-2010.
  • Capel, F., E. Klimcakova, et al. (2009). "Macrophages and adipocytes in human obesity: adipose tissue gene expression and insulin sensitivity during calorie restriction and weight stabilization." Diabetes 58(7): 1558-1567.
  • Ennequin, G., F. Capel, F et al. (2017). "Neuregulin 1 improves complex 2-mediated mitochondrial respiration in skeletal muscle of healthy and diabetic mice." Sci Rep 7(1): 1742.
  • Pinel, A., E. Pitois, et al. (2016). "EPA prevents fat mass expansion and metabolic disturbances in mice fed with a Western diet." J Lipid Res.
  • Pinel, A., J. P. Rigaudiere, et al. (2015). "N-3PUFA differentially modulate palmitate-induced lipotoxicity through alterations of its metabolism in C2C12 muscle cells." Biochim Biophys Acta.

Curriculum Vitae

Since 2010: INRA, Unité de Nutrition Humaine, Clermont-Ferrand-Theix, France

2008-10: Institut de Recherches Servier, Croissy-sur-Seine, France.

2005-08: INSERM U858 - Unité de Recherches sur les Obésités, Toulouse, France

2001-04: PhD, INRA, Unité de Nutrition et Métabolisme Protéique, Clermont-Ferrand-Theix, France

Research programs funded by IEED GENESYS P.I.V.E.R.T (3 programs 2013-2017), Avril, European FP7 program (NuAge -2016), ANSSD program of INRA (2011-2012) région Auvergne-FEDER (Prix nouveau chercheur 2015-2017 Région Auvergne)