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24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

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Human Nutrition Unit

Zone de texte éditable et éditée et rééditée


Activités de recherche

Email: contact
Tél: +33 (0)4 73 60 82 67


Engineer, Manager of the Technical Platform "Indirect Calorimetry", and developer of computer applications.


The technical platform is a common resource that includes facilities located on two sites:


* 2 Calorimetric Chambers of 10 m² located in Clermont Ferrand at CRNH d'Auvergne. They allow calculations of energy expenditure and human RQ continuously over long periods of time, based on measurements of respiratory exchanges (Indirect Calorimetry), in the following areas:

    - accurate calculation of the energy balance over 24h from the monitoring of inputs and expenses

    - determination of the kinetics of energy expenditure

    - evaluation of the nutritional needs of a specific population (eg athletes)

    - determination of metabolic disturbances

    - study of the thermogenic properties of nutrients, medicines and nutritional formulas (diets)

    - Exploration of energy expenditure under usual conditions of life

The calorimetric chambers allow to accurately estimate the energy expenditure and the use of energy substrates (proteins, lipids, carbohydrates) of an individual living under conditions allowing precise control of his physical activity and diet.


* 4 Calorimetric cages for rats or mice located at the UNH animal facility at the INRA site in Theix. The principle of measuring the energy expenditure of rats and mice is here also based on indirect calorimetry.


The management of these facilities and the exploitation of the data generated require the development of specific programs, particularly in VBA and Matlab.


  • Le Bacquer O, Combe K, Montaurier C, Salles J, Giraudet C, Patrac V, Domingues-Faria C, Guillet C, Louche K, Boirie Y, Sonenberg N, Moro C, Walrand S. Muscle metabolic alterations induced by genetic ablation of 4E-BP1 and 4E-BP2 in response to diet-induced obesity. Mol Nutr Food Res. 2017 Sep;61(9).
  • Chavanelle V, Boisseau N, Otero YF, Combaret L, Dardevet D, Montaurier C, Delcros G, Peltier SL & Sirvent P. Effects of high-intensity interval training and moderate-intensity continuous training on glycaemic control and skeletal muscle mitochondrial function in db/db mice. Sci Rep. 2017 Mar 16;7(1):204. doi: 10.1038/s41598-017-00276-8.
  • Pinel A, Pitois E, Rigaudiere JP, Jouve C, De Saint-Vincent S, Laillet B, Montaurier C, Huertas A, Morio B & Capel F. EPA prevents fat mass expansion and metabolic disturbances in mice fed with a Western diet. J Lipid Res. 2016 Jun 15. pii: jlr.M06
  • Ennequin G, Boisseau N, Caillaud K, Chavanelle V, Etienne M, Li X, Montaurier C, Sirvent P. Neuregulin 1 affects leptin levels, food intake and weight gain in normal-weight, but not obese, db/db mice. Diabetes Metab. 2015 Jan 5. pii: S1262-3636(14)00197-9. doi: 10.1016/j.diabet.2014.12.002.
  • Heng AE, Montaurier C, Cano N, Caillot N, Blot A, Meunier N, Pereira B, Marceau G, Sapin V, Jouve C, Boirie Y, Deteix P, Morio B. Energy expenditure, spontaneous physical activity and with weight gain in kidney transplant recipients. Clin Nutr. 2014 May 15. pii: S0261-5614(14)00134-4. doi: 10.1016/j.clnu.2014.05.003.
  • Montaurier C, Morio B, Bannier S, Derost P, Arnaud P, Brandolini-Bunlon M, Giraudet C, Boirie Y, Durif F. Mechanisms of body weight gain in patients with Parkinson's disease after subthalamic stimulation. Brain. 2007 Jul;130(Pt 7):1808-18. Epub 2007 May 29.