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24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal logo Université Clermont Auvergne & associés

Human Nutrition Unit

Zone de texte éditable et éditée et rééditée

Scientific production

PFEM team's Publications

°PhD and Post-doc contribution
(D: method development, C: collaborative projects, S: scientific activity component)


Monnerie S°, Petera M, Lyan B, Gaudreau P, Comte B, Pujos-Guillot E. Analytic Correlation Filtration: A New Tool to Reduce Analytical Complexity of Metabolomic Datasets. Metabolites. 2019 Oct 24;9(11). pii: E250. doi: 10.3390/metabo9110250. - D

Brandolini-Bunlon M, Pétéra M, Gaudreau P, Comte B, Bougeard S, Pujos-Guillot E. Multi-block PLS discriminant analysis for the joint analysis of metabolomic and epidemiological data. Metabolomics. 2019 Oct 3;15(10):134. doi: 10.1007/s11306-019-1598-y. - D

Borgsmüller N, Gloaguen Y, Opialla T, Blanc E, Sicard E, Royer AL, Le Bizec B, Durand S, Migné C, Pétéra M, Pujos-Guillot E, Giacomoni F, Guitton Y, Beule D, Kirwan J. WiPP: Workflow for Improved Peak Picking for Gas Chromatography-Mass Spectrometry (GC-MS) Data. Metabolites. 2019 Aug 21;9(9). pii: E171. doi: 10.3390/metabo9090171. - D

Vázquez-Manjarrez N, Weinert CH, Ulaszewska MM, Mack CI, Micheau P, Pétéra M, Durand S, Pujos-Guillot E, Egert B, Mattivi F, Bub A, Dragsted LO, Kulling SE, Manach C. Discovery and Validation of Banana Intake Biomarkers Using Untargeted Metabolomics in Human Intervention and Cross-sectional Studies. J Nutr. 2019 Oct 1;149(10):1701-1713. doi: 10.1093/jn/nxz125. - C

Low DY, Lefèvre-Arbogast S, González-Domínguez R, Urpi-Sarda M, Micheau P, Petera M, Centeno D, Durand S, Pujos-Guillot E, Korosi A, Lucassen PJ, Aigner L, Proust-Lima C, Hejblum BP, Helmer C, Andres-Lacueva C, Thuret S, Samieri C, Manach C. Diet-Related Metabolites Associated with Cognitive Decline Revealed by Untargeted Metabolomics in a Prospective Cohort. Mol Nutr Food Res. 2019 Sep;63(18):e1900177. doi: 10.1002/mnfr.201900177. Epub 2019 Jul 9. - C

Lécuyer L, Dalle C, Lyan B, Demidem A, Rossary A, Vasson MP, Petera M, Lagree M, Ferreira T, Centeno D, Galan P, Hercberg S, Deschasaux M, Partula V, Srour B, Latino-Martel P, Kesse-Guyot E, Druesne-Pecollo N, Durand S, Pujos-Guillot E, Touvier M. Plasma Metabolomic Signatures Associated with Long-term Breast Cancer Risk in the SU.VI.MAX Prospective Cohort. Cancer Epidemiol Biomarkers Prev. 2019 Aug;28(8):1300-1307. doi: 10.1158/1055-9965.EPI-19-0154. Epub 2019 Jun 4. - C

Damont A, Olivier MF, Warnet A, Lyan B, Pujos-Guillot E, Jamin EL, Debrauwer L, Bernillon S, Junot C, Tabet JC, Fenaille F. Proposal for a chemically consistent way to annotate ions arising from the analysis of reference compounds under ESI conditions: A prerequisite to proper mass spectral database constitution in metabolomics. J Mass Spectrom. 2019 Jun;54(6):567-582. doi: 10.1002/jms.4372. - D

Ulaszewska MM, Weinert CH, Trimigno A, Portmann R, Andres Lacueva C, Badertscher R, Brennan L, Brunius C, Bub A, Capozzi F, Cialie Rosso M, Cordero CE, Daniel H, Durand S, Egert B, Ferrario PG, Feskens EJM, Franceschi P, Garcia-Aloy M, Giacomoni F, Giesbertz P, Gonzalez-Dominguez R, Hanhineva K, Hemeryck LY, Kopka J, Kulling SE, Llorach R, Manach C, Mattivi F, Migné C, Munger LH, Ott B, Picone G, Pimentel G, Pujos-Guillot E, Riccadonna S, Rist MJ, Rombouts C, Rubert J, Skurk T, Sri Harsha PSC, Van Meulebroek L, Vanhaecke L, Vazquez-Fresno R, Wishart D and Vergeres G (2019). Nutrimetabolomics: An Integrative Action for Metabolomic Analyses in Human Nutritional Studies. Molecular Nutrition & Food Research. 63. - C

Pujos-Guillot E, Pétéra M, Jacquemin J, Centeno D, Lyan B, Montoliu I, Madej D, Pietruszka B, Fabbri C, Santoro A, Brzozowska A, Franceschi C, Comte B (2019). Identification of Pre-frailty Sub-Phenotypes in Elderly Using Metabolomics. Frontiers in Physiology. 9.1903. - S

Lécuyer L, Dalle C, Lyan B, Demidem A, Rossary A, Vasson M-P, Petera M, Lagree M, Ferreira T, Centeno D, Galan P, Hercberg S, Deschasaux M, Partula V, Srour B, Latino-Martel P, Kesse-Guyot E, Druesne-Pecollo N, Durand S, Pujos-Guillot E, and Touvier M (2019). Plasma metabolomic signatures associated with long-term breast cancer risk in the SU.VI.MAX prospective cohort. Cancer Epidemiology, Biomarkers & Prevention. - C

Dao MC, Sokolovska N, Brazeilles R, Affeldt S, Pelloux V, Prifti E, Chilloux J, Verger EO, Kayser BD, Aron-Wisnewsky J, Ichou F, Pujos-Guillot E, Hoyles L, Juste C, Dore J, Dumas ME, Rizkalla SW, Holmes BA, Zucker JD, Clement K (2019). A Data Integration Multi-Omics Approach to Study Calorie Restriction-Induced Changes in Insulin Sensitivity. Frontiers in Physiology. 9. 1958. - S

Mohamed AB, Remond D, Chambon C, Sayd T, Hébraud M, Capel F, Cohade B, Hafnaoui N, Bechet D, Coudy-Gandilhon C, Migne C, David J, Dardevet D, Dore J, Polakof S, Savary-Auzeloux I (2019). A mix of dietary fermentable fibers improves lipids handling by the liver of overfed minipigs. Journal of Nutritional Biochemistry.65:72-82. - C


Khoury S, Pouyet C, Lyan B and Pujos-Guillot E (2018). Evaluation of oxidized phospholipids analysis by LC-MS/MS. Analytical and Bioanalytical Chemistry.410(2):633-647. - D

Pujos-Guillot E, Brandolini-Bunlon M, Fouillet H, Joly C, Martin JF, Huneau JF, Dardevet D and Mariotti F (2018). Metabolomics Reveals that the Type of Protein in a High-Fat Meal Modulates Postprandial Mitochondrial Overload and Incomplete Substrate Oxidation in Healthy Overweight Men. Journal of Nutrition.148(6):876-884. - C

Gatineau E, Capel F, Dardevet D, David J, Pouyet C, Polakof S and Mosoni L (2018). Effect of high chronic intake of sucrose on liver metabolism in aging rats. Modulation by rutin and micronutrients. Journal of Physiology and Biochemistry.1-9. - C

Gatineau E, Cluzet S, Krisa S, Papet I, Migné C, Rémond D, Dardevet D, Polakof S, Richard T and Mosoni L (2018). Effects of nutritional state, aging and high chronic intake of sucrose on brain protein synthesis in rats: modulation of it by rutin and other micronutrients. Food & Function.9(5):2922-2930. - C

Jarzaguet M, Polakof S, David J, Migné C, Joubrel G, Efstathiou T, Rémond D, Mosoni L and Dardevet D (2018). A meal with mixed soy/whey proteins is as efficient as a whey meal in counteracting the age-related muscle anabolic resistance only if the protein content and leucine levels are increased. Food & Function.9(12):6526-6534. - C

Jousse C, Dalle C, Canet I, Lagrée M, Traïkia M, Lyan B, Mendes C, Sancelme M, Amato P and Delort A-M (2018). Metabolomic study of the response to cold shock in a strain of Pseudomonas syringae isolated from cloud water. Metabolomics.14(1):11. - C

Koistinen VM, da Silva AB, Abranko L, Low D, Villalba RG, Barberan FT, Landberg R, Savolainen O, Alvarez-Acero I, de Pascual-Teresa S, Van Poucke C, Almeida C, Petraskova L, Valentova K, Durand S, Wiczkowski W, Szawara-Nowak D, Gonzalez-Dominguez R, Llorach R, Andres-Lacueva C, Aura AM, Seppanen-Laakso T, Hanhineva K, Manach C and Bronze MR (2018). Interlaboratory Coverage Test on Plant Food Bioactive Compounds and Their Metabolites by Mass Spectrometry-Based Untargeted Metabolomics. Metabolites.8(3) (no statistic) - D

Martin OCB, Naud N, Tache S, Debrauwer L, Chevolleau S, Dupuy J, Chantelauze C, Durand D, Pujos-Guillot E, Blas-Y-Estrada F, Urbano C, Kuhnle GGC, Sante-Lhoutellier V, Sayd T, Viala D, Blot A, Meunier N, Schlich P, Attaix D, Gueraud F, Scislowski V, Corpet DE and Pierre FHF (2018). Targeting Colon Luminal Lipid Peroxidation Limits Colon Carcinogenesis Associated with Red Meat Consumption. Cancer Prevention Research.11(9):569-580. - S

Meale SJ, Morgavi DP, Cassar-Malek I, Andueza D, Ortigues-Marty I, Robins R, Schiphorst AM, Migné C, Pétéra M, Laverroux S, Graulet B, Boudra H and Cantalapiedra-Hijar G (2018). Exploration of Biological Markers of Feed Efficiency in Young Bulls (vol 65, pg 9817, 2017). Journal of Agricultural and Food Chemistry.66(17):4580-4580. - C

Polakof S, Rémond D, Bernalier-Donadille A, Rambeau M, Pujos-Guillot E, Comte B, Dardevet D and Savary-Auzeloux I (2018). Metabolic adaptations to HFHS overfeeding: how whole body and tissues postprandial metabolic flexibility adapt in Yucatan mini-pigs. European Journal of Nutrition.57(1):119-135. - S

Santos T, Théron L, Chambon C, Viala D, Centeno D, Esbelin J and Hebraud M (2018). MALDI mass spectrometry imaging and in situ microproteomics of Listeria monocytogenes biofilms. Journal of Proteomics.187:152-160. - D

Collino S, Comte B, Pujos-Guillot E, Franceschi C, Kussmann M. (2018) Healthy ageing phenotypes and trajectories. In: Oxford Textbook of Geriatric Medicine, 3e. J-P Michel, B. Lynn Beatty, Finbarr C Martin and Jeremy Waltson (eds).

Migné C, Durand S, Pujos-Guillot E. (2018). Exploratory GC/MS-Based Metabolomics of Body Fluids. In: Martin Giera, dir., Clinical Metabolomics : Methods and Protocols (p. 239-246). Methods in Molecular Biology (Chapter 16). Springer. 384 p., DOI : 10.1007/978-1-4939-7592-1_16


Buffière C, Gaudichon C, Hafnaoui N, Migné C, Scislowsky V, Khodorova N, Mosoni L, Blot A, Boirie Y, Dardevet D, Sante-Lhoutellier V and Rémond D (2017). In the elderly, meat protein assimilation from rare meat is lower than that from meat that is well done. American Journal of Clinical Nutrition.106(5):1257-1266. - C

Centeno D, Venien A, Pujos-Guillot E, Astruc T, Chambon C and Théron L (2017). Myofiber metabolic type determination by mass spectrometry imaging. Journal of Mass Spectrometry 52(8):493-496. - D

Guitton Y, Tremblay-Franco M, Le Corguille G, Martin JF, Pétera M, Roger-Mele P, Delabriere A, Goulitquer S, Monsoor M, Duperier C, Canlet C, Servien R, Tardivel P, Caron C, Giacomoni F and Thevenot EA (2017). Create, run, share, publish, and reference your LC-MS, FIA-MS, GC-MS, and NMR data analysis workflows with the Workflow4Metabolomics 3.0 Galaxy online infrastructure for metabolomics. International Journal of Biochemistry & Cell Biology.93:89-101. - D

Pujos-Guillot E, Brandolini M, Pétéra M, Grissa D, Joly C, Lyan B, Herquelot E, Czernichow S, Zins M, Goldberg M and Comte B (2017). Systems Metabolomics for Prediction of Metabolic Syndrome. Journal of Proteome Research.16(6):2262-2272. - S

Chanet A, Salles J, Guillet C, Giraudet C, Berry A, Patrac V, Domingues-Faria C, Tagliaferri C, Bouton K, Bertrand-Michel J, Van Dijk M, Jourdan M, Luiking Y, Verlaan S, Pouyet C, Denis P, Boirie Y and Walrand S (2017). Vitamin D supplementation restores the blunted muscle protein synthesis response in deficient old rats through an impact on ectopic fat deposition. The Journal of Nutritional Biochemistry.46:30-38. - C

Chanet A, Verlaan S, Salles J, Giraudet C, Patrac V, Pidou V, Pouyet C, Hafnaoui N, Blot A, Cano N, Farigon N, Bongers A, Jourdan M, Luiking Y, Walrand S and Boirie Y (2017). Supplementing breakfast with a vitamin D and leucine-enriched whey protein medical nutrition drink enhances postprandial muscle protein synthesis and muscle mass in healthy older men. Journal of Nutrition.147(12):2262-2271. - C

Mast C, Pourpe C, Voyard G, Rémond D, Migné C, Centeno D, Dardevet D, Savary-Auzeloux I and Papet I (2017). Dietary supplementation with cysteine prevents adverse metabolic outcomes of repeated cures with paracetamol in old rats. Br J Nutr.1-8. - C

Revel A, Jarzaguet M, Peyron MA, Papet I, Hafnaoui N, Migné C, Mosoni L, Polakof S, Savary-Auzeloux I, Rémond D and Dardevet D (2017). At same leucine intake, a whey/plant protein blend is not as effective as whey to initiate a transient post prandial muscle anabolic response during a catabolic state in mini pigs. PLoS One.12(10). - C

Salles J, Chanet A, Berry A, Giraudet C, Patrac V, Domingues-Faria C, Rocher C, Guillet C, Denis P, Pouyet C, Bonhomme C, Ruyet PL, Rolland Y, Boirie Y and Walrand S (2017). Fast digestive, leucine-rich, soluble milk proteins improve muscle protein anabolism and mitochondrial function in undernourished old rats. Molecular Nutrition & Food Research.61(11) - C

Tottey W, Feria-Gervasio D, Gaci N, Laillet B, Pujos E, Martin JF, Sébédio JL, Sion B, Jarrige JF, Alric M and Brugere JF (2017). Colonic Transit Time Is a Driven Force of the Gut Microbiota Composition and Metabolism: In Vitro Evidence. J Neurogastroenterol Motil.23(1):124-134. - S

Van Rijswijk M, Beirnaert C, Caron C, Cascante M, Dominguez V, Dunn WB, Ebbels TMD, Giacomoni F, Gonzalez-Beltran A, Hankemeier T, Haug K, Izquierdo-Garcia JL, Jimenez RC, Jourdan F, Kale N, Klapa MI, Kohlbacher O, Koort K, Kultima K, Le Corguille G, Moschonas NK, Neumann S, O'Donovan C, Reczko M, Rocca-Serra P, Rosato A, Salek RM, Sansone SA, Satagopam V, Schober D, Shimmo R, Spicer RA, Spjuth O, Thevenot EA, Viant MR, Weber RJM, Willighagen EL, Zanetti G and Steinbeck C (2017). The future of metabolomics in ELIXIR (version 1 + 2). F1000 Research.6 (no statistic) - D


Grissa D, Pétéra M, Brandolini M, Napoli A, Comte B and Pujos-Guillot E (2016). Feature Selection Methods for Early Predictive Biomarker Discovery Using Untargeted Metabolomic Data. Frontiers in Molecular Biosciences.3(30):15. (no statistic) - S

Delosiere M, Sante-Lhoutellier V, Chantelauze C, Durand D, Thomas A, Joly C, Pujos-Guillot E, Rémond D, Comte B, Gladine C, Guy A, Durand T, Laurentie M and Dufour C (2016). Quantification of 4-hydroxy-2-nonenal-protein adducts in the in vivo gastric digesta of mini-pigs using a GC-MS/MS method with accuracy profile validation. Food & Function.7(8):3497-3504. - C

Mast C, Savary-Auzeloux I, Rémond D, Pouyet C, Centeno D, Voyard G, Combaret L, Dardevet D and Papet I (2016). Repeated cures with paracetamol worsen sarcopenia in old rats with suboptimal food intake. Journal of physiology and pharmacology.67(5):759-768. - C

Matta J, Carette C, Levy Marchal C, Bertrand J, Pétéra M, Zins M, Pujos-Guillot E, Comte B and Czernichow S (2016). Weight for gestational age and metabolically healthy obesity in adults from the Haguenau cohort. Bmj Open.6(8):e011367. - S

Matta J, Carette C, Levy Marchal C, Bertrand J, Pétéra M, Zins M, Pujos-Guillot E, Comte B and Czernichow S (2016). Dietary intake in young adults born small or appropriate for gestational age: data from the Haguenau cohort. Bmj Open.6(7):e012309. - S

Nurit E°, Lyan B, Pujos-Guillot E, Branlard G and Piquet A (2016). Change in B and E vitamin and lutein, beta-sitosterol contents in industrial milling fractions and during toasted bread production. Journal of Cereal Science.69:290-296. - D

Philippe C, Wauquier F, Lyan B, Coxam V and Wittrant Y (2016). GPR40, a free fatty acid receptor, differentially impacts osteoblast behavior depending on differentiation stage and environment. Molecular and Cellular Biochemistry.412(1-2):197-208. - C

Pinel A, Rigaudière JP, Laillet B, Pouyet C, Malpuech-Brugère C, Prip-Buus C, Morio B and Capel F (2016). N-3PUFA differentially modulate palmitate-induced lipotoxicity through alterations of its metabolism in C2C12 muscle cells. BBA Molecular and Cell Biology of Lipids.1861(1):12-20. - C

Polakof S, Dardevet D, Lyan B, Mosoni L, Gatineau E, Martin JF, Pujos-Guillot E, Mazur A and Comte B (2016). Time Course of Molecular and Metabolic Events in the Development of Insulin Resistance in Fructose-Fed Rats. Journal of Proteome Research.15(6):1862-1874.  - S

Surya R, Helies-Toussaint C, Martin OC, Gauthier T, Gueraud F, Tache S, Naud N, Jouanin I, Chantelauze C, Durand D, Joly C, Pujos-Guillot E, Pierre FH and Huc L (2016). Red meat and colorectal cancer: Nrf2-dependent antioxidant response contributes to the resistance of preneoplastic colon cells to fecal water of hemoglobin- and beef-fed rats. Carcinogenesis.37(6):635-645. - C

Tatar Z, Migné C, Pétéra M, Gaudin P, Lequerre T, Marotte H, Tebib J, Pujos Guillot E and Soubrier M (2016). Variations in the metabolome in response to disease activity of rheumatoid arthritis. BMC Musculoskelet Disord.17(1):353. - C

Théron L, Centeno D, Coudy-Gandilhon C, Pujos-Guillot E, Astruc T, Rémond D, Barthelemy JC, Roche F, Feasson L, Hebraud M, Béchet D and Chambon C (2016). A Proof of Concept to Bridge the Gap between Mass Spectrometry Imaging, Protein Identification and Relative Quantitation: MSI similar to LC-MS/MS-LF. Proteomes.4(4)(no statistic) - D

Walrand S, Gryson C, Salles J, Giraudet C, Migné C, Bonhomme C, Le Ruyet P and Boirie Y (2016). Fast-digestive protein supplement for ten days overcomes muscle anabolic resistance in healthy elderly men. Clinical Nutrition.35(3):660-668. - C

Publications on PubMed