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Phylogenetic and Functional Diversity of Fungal Heme Peroxidases (PeroxiDiv)

Microbiote intestinal et maladies métaboliques chez l’Homme : un système digestif in vitro unique pour catalyser le développement de stratégies nutritionnelles innovantes

De nos jours, le régime occidental pauvre en fibres est associé avec le développement de nombreuses pathologies, probablement en relation avec une perturbation (ou dysbiose) du microbiote intestinal. Plusieurs études ont montré les effets bénéfiques des fibres sur la santé humaine, tels qu’une restauration des équilibres microbiens et une diminution de l’inflammation.

Mycotoxins are toxic secondary metabolites produced by a range of fungi and are common contaminants of agricultural crops. These toxins are stable and able to remain active for long periods while withstanding most agricultural decontamination processes. Consequently, mycotoxins are able to enter into the food chain. Many of these mycotoxins have the capacity to cause numerous adverse health effects. Of the currently more than 300 known mycotoxins, the Fusarium toxins that have the largest adverse impact on human and animal health are deoxynivalenol (DON), zearalenone and fumonisin B. Among them, DON is the most prevalent one with a incidence rate of 59 and 43% in raw and processed cereal products respectively. In France, around 1% of adults and between 5 and 10% of children are exposed to DON at levels greater than the toxicological threshold of 1μg/kg bw/d.

Sensibilité au gluten chez le sportif de haut niveau